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Suvorexant | C23H23ClN6O2 - PubChem
Suvorexant is an orexin receptor antagonist used for the treatment of insomnia and sleep disorders. Suvorexant therapy is associated with rare occurrence of transient serum enzyme elevations, but has not been implicated in cases of clinically apparent liver injury.
Suvorexant | Patents | Expiry | Expiration | Dates ...
Patents Listed in the FDA Orange Book Drug Database of Suvorexant with information and expiry/expiration dates. Information, Expiry & Status of FDA Orange Book Patents covering Suvorexant. Please Wait.
WO2018118929A1 - patents.google.com
Suvorexant may be taken with or without food; however for faster sleep onset, Suvorexant should not be administered with or soon after a meal.  The mean volume of distribution of Suvorexant is approximately 49 liters. Suvorexant is extensively bound ( > 99%) to human plasma proteins and does not preferentially distribute into red blood cells.
Suvorexant - DrugBank
Suvorexant is a selective dual antagonist of orexin receptors OX1R and OX2R that promotes sleep by reducing wakefulness and arousal. It has been approved for the treatment of insomnia.
US Patent Application for CHIRAL RESOLUTION OF AN ...
Suvorexant has one chiral center with a configuration (R). The synthesis of suvorexant is described in the patent family of WO2008069997A1 and in Cox et al., J. Med. Chem.
Merck & Co., Inc. - Merck’s BELSOMRA® (suvorexant) C-IV ...
BELSOMRA (suvorexant) is a first-in-class oral, highly selective antagonist for orexin receptors. Orexin is a neurotransmitter found in a specific part of the brain that can help keep a person awake.
BELSOMRA Loss of Exclusivity (LOE). When do the patents on ...
Belsomra is a drug marketed by Merck Sharp Dohme and is included in one NDA. There is one patent protecting this drug. This drug has fifty-four patent family members in thirty-five countries. The generic ingredient in BELSOMRA is suvorexant. One supplier is listed for this compound. Additional details are available on the suvorexant profile page.
BELSOMRA® suvorexant Tablets - fda.gov
BELSOMRA is a prescription medicine for adults who have trouble falling or staying asleep (insomnia). It is not known if BELSOMRA is safe and effective in children under the age of 18.
Suvorexant - Wikipedia
Suvorexant, sold under the trade name Belsomra, is a medication for the treatment of insomnia. It is effective for insomnia, at least for four weeks and as compared to a placebo. Suvorexant is a selective, dual orexin receptor antagonist (DORA) made by Merck & Co.
Belsomra: Uses, Dosage, Side Effects & Warnings - Drugs.com
Belsomra (suvorexant) is a sleep medicine that helps regulate your sleep and wake cycle. Belsomra is used to treat insomnia (trouble falling asleep or staying asleep). Belsomra may also be used for purposes not listed in this medication guide.
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