Suvorexant Osa

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Belsomra (suvorexant): Sleep Aid Warnings, Side Effects ...

Summary. Belsomra (suvorexant) is a member of the hypnotic class of drugs used to treat insomnia. Side effects, drug interactions, warnings and precautions, and pregnancy safety information should be reviewed prior to taking any medication.
https://www.medicinenet.com/suvorexant_belsomra/article.htm

Effects of Suvorexant, an Orexin Receptor Antagonist, on ...

The orexin receptor antagonist suvorexant (MK-4305) has been shown to be effective for the treatment of insomnia in previous clinical trials at doses of 10, 20, or 40 mg in non-elderly patients and 15 or 30 mg in elderly patients. The maximum recommended dose approved in the USA and Japan is 20 mg once daily.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702197/

Belsomra: Uses, Dosage, Side Effects & Warnings - Drugs.com

Belsomra (suvorexant) is a sleep medicine that helps regulate your sleep and wake cycle. Belsomra is used to treat insomnia (trouble falling asleep or staying asleep). Belsomra may also be used for purposes not listed in this medication guide.
https://www.drugs.com/belsomra.html

Single-use suvorexant for treating insomnia during ...

Suvorexant is a dual orexin receptor antagonist. Orexin neurons originate in the lateral hypothalamus and project throughout the brain, including respiratory centers in the brain stem, 26 suggesting the association of orexin and respiration.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400124/

[Full text] Single-use suvorexant for treating insomnia ...

Effects of suvorexant on sleep apnea in patients with ...

Thus, suvorexant induces sleep by inhibiting stimulation of the nerve nucleus, which is controlled by orexin neuron and whose action is to maintain wakefulness. Suvorexant antagonizes orexin, whose action is limited in the sleep/wake transition, and does not suppress the whole activity broadly as do GABA receptor agonists, such as benzodiazepines.
https://www.sciencedirect.com/science/article/pii/S0914508719300085

Single-use suvorexant for treating insomnia during ...

The aim of this study was to investigate the safety and efficacy of a new hypnotic agent, suvorexant, a dual orexin receptor antagonist, for insomnia in suspected OSA patients during in-laboratory PSG.
https://www.ncbi.nlm.nih.gov/pubmed/30880914

HIGHLIGHTS OF PRESCRIBING INFORMATION BELSOMRA safely and ...

BELSOMRA® (suvorexant) is indicated for the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance. 2 DOSAGE AND ADMINISTRATION 2.1 Dosing Information Use the lowest dose effective for the patient. The recommended dose for BELSOMRA is 10 mg, taken no more than once per night and within 30
https://www.merck.com/product/usa/pi_circulars/b/belsomra/belsomra_pi.pdf

Effects of Suvorexant in Participants With Obstructive ...

The AHI is an overall index of obstructive sleep apnea (OSA) severity. The AHI is calculated by dividing the number of apneas and hypopneas by the number of hours of sleep. AHI values are categorized as mild OSA = 5 to <15/hr and moderate OSA = 15 to <30/hr.
https://clinicaltrials.gov/ct2/show/NCT01300455

BELSOMRA® (suvorexant) C-IV | Official Website

BELSOMRA is a controlled substance because it can be abused or cause dependence. Before taking BELSOMRA, tell your doctor about all of your medical conditions, including if you: have a history of depression, mental illness, or suicidal thoughts
https://www.belsomra.com/

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